袁小青，医学博士，副研究员，中山大学青年学术骨干人才，中山大学孙逸仙纪念医院课题组负责人。中山大学孙逸仙纪念医院尊龙凯时-人生就是搏医学研究中心副主任（主持工作）；省市共建恶性肿瘤发病机制及精准诊疗广东省重点实验室常务副主任。
主要从事疾病（包括但不限于肿瘤）微环境的表观互作与细胞死亡方面的机制研究，致力于开发基于系统筛选的新型疾病标志物和药物靶点，研究领域涉及生物信息学、表观遗传学（比如超级增强子和长链非编码RNA）、染色体外环状DNA(eccDNA/ecDNA)、调节性细胞死亡、肿瘤免疫和代谢等。近五年以通讯作者或第一作者在 Oncogene（杂志2022年度最佳论文）、Nucleic Acids Research（ESI高被引论文和热点论文）、Molecular Therapy（封面论文）、Acta Pharmaceutica Sinica B和Cancer Research等国际专业期刊发表高水平SCI论文15篇。主持国家自然科学基金、广东省自然科学基金青年提升项目等省部级以上项目多项。申请国家发明专利4项（其中3项已获授权），并获计算机软件著作权1项。同时，担任中国药理学会药物基因组学专业委员会委员和Signal Transduction and Targeted Therapy、Briefings in Bioinformatics、Clinical and Translational Medicine等多个国际期刊特邀审稿人；入选广东省高层次人才评审专家，并受邀担任广东省自然科学基金和浙江省自然科学基金等项目通讯评审专家。
发表论文 (#第一作者，*通讯作者)：
（1） Li Peng*; Nan Zhou; Chao-Yang Zhang; Guan-Cheng Li; Xiao-Qing Yuan*. eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancers. Oncogene, 2022, 41(19):2696-2705. (期刊论文，2022年度最佳论文)
（2） Xiao-Qing Yuan#, Nan Zhou#, Jun-Pu Wang#, Xian-Zhu Yang, Shan Wang, Chao-Yang Zhang, Guan-Cheng Li, Li Peng*. Anchoring super-enhancer-driven oncogenic lncRNAs for anti-tumor therapy in hepatocellular carcinoma, Molecular Therapy, 2023 Jun 7;31(6):1756-1774. (期刊论文，封面文章)
（3） Li Peng; Yanyi Jiang; Hengxing Chen; Yongqiang Wang; Qiusheng Lan; Shuiqin Chen; Zhanwang Huang; Jingyuan Zhang; Duanqing Tian; Yuntan Qiu; Diankui Cai; Jiangyun Peng; Daning Lu; Xiaoqing Yuan*; Xianzhu Yang*; Dong Yin*. Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma. Acta Pharmaceutica Sinica B, 2024, http://doi.org/10.1016/j.apsb.2024.02.025. (期刊论文)
（4） Nan Zhou#, Xiaoqing Yuan#, Qingsong Du#, Zhiyu Zhang, Xiaolei Shi, Jinku Bao*, Yuping Ning*, Li Peng*. FerrDb V2: update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations, Nucleic Acids Research, 2023, 51(D1): D571-D582. (期刊论文，ESI高被引和热点论文)
（5） Yuan, Xiao Qing#; Chen, Peng#; Du, Yin Xiao; Zhu, Ke Wei; Zhang, Dao Yu; Yan, Han; Liu, Han; Liu, Yan Ling; Cao, Shan; Zhou, Gan; Zeng, Hui; Chen, Shu Ping; Zhao, Xie Lan; Yang, Jing; Zeng, Wen Jing; Chen, Xiao Ping. Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients. Journal of Translational Medicine, 2019, 17(1): 220. (期刊论文)
（6） Xiaoqing Yuan; Li Peng; Jianing Chen; Xiuying Cui; Yujie Liu; Erwei Song. Super enhancer-associated lincRNA BCSL1 promotes the development of breast cancer [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Research 2020; 80(16 Suppl): Abstract nr 4825. (AACR会议摘要)
（7） Li Peng; Jiang-Yun Peng; Dian-Kui Cai; Yun-Tan Qiu; Qiu-Sheng Lan; Jie Luo; Bing Yang; Hai-Tao Xie; Ze-Peng Du; Xiao-Qing Yuan*; Yue Liu*; Dong Yin*. Immune Infiltration and Clinical Outcome of Super-Enhancer-Associated lncRNAs in Stomach Adenocarcinoma. Frontier in Oncology, 2022, 12: 780493. (期刊论文,邀稿)
（8） Li Peng; Binyuan Jiang; Xiaoqing Yuan; Yuntan Qiu; Jiangyun Peng; Yongsheng Huang; Chaoyang Zhang; Yin Zhang; Zhaoyu Lin; Jinsong Li; Weicheng Yao; Weixi Deng; Yaqin Zhang; Meng Meng; Xi Pan; Chunquan Li; Dong Yin; Xinyu Bi; Guancheng Li*; De-Chen Lin*. Super-Enhancer-Associated Long Noncoding RNA HCCL5 Is Activated by ZEB1 and Promotes the Malignancy of Hepatocellular Carcinoma. Cancer Research, 2019, 79(3): 572-584. (期刊论文，ESI高被引论文)
（9） Zongjiang Zhou; Jinghe Li; Diabate Ousmane; Li Peng*; Xiaoqing Yuan*; Junpu Wang*. Metabolic reprogramming directed by super-enhancers in tumors: An emerging landscape. Molecular Therapy, 2024, 32(3):572-579. (期刊论文)
（10） Yimin Guo#; Xiaoqing Yuan# (共一第二); Luna Hong; Qiujie Wang; Shanying Liu; Zhaolin Li; Linjie Huang; Shanping Jiang; Jianting Shi. Promotor Hypomethylation Mediated Upregulation of miR-23b-3p Targets PTEN to Promote Bronchial Epithelial-Mesenchymal Transition in Chronic Asthma. Frontiers in Immunology, 2022, 12: 771216 (期刊论文)
（11）Diankui Cai#; Xiaoqing Yuan#; D. Q. Cai#; Ang Li; Sijia Yang; Weibang Yang; Jinxin Duan; Wenfeng Zhuo; Jun Min; Li Peng; Jinxing Wei. Integrative analysis of lactylation-related genes and establishment of a novel prognostic signature for hepatocellular carcinoma. Journal of Cancer Research and Clinical Oncology, 2023, 149(13):11517-11530. (期刊论文)
（12）Jiahui Zhang; Nanyan Miao; Liyan Lao; Wen Deng; Jiawen Wang; Xiaofeng Zhu; Yongsheng Huang; Huayue Lin; Wenfeng Zeng; Wei Zhang; Luyuan Tan; Xiaoqing Yuan; Xin Zeng; Jingkun Zhu; Xueman Chen; Erwei Song; Linbin Yang; Yan Nie; Di Huang. Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal-like Breast Cancer. Advanced Science, 2024 Mar 16:e2307660. doi: 10.1002/advs.202307660.（期刊论文）
(13) Jiang-Yun Peng, Dian-Kui Cai, Ren-Li Zeng, Chao-Yang Zhang, Guan-Cheng Li, Si-Fan Chen, Xiao-Qing Yuan, Li Peng. Upregulation of Superenhancer-Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma. Advanced Science. 2022 Oct 28; e2204711. DOI: 10.1002/advs.202204711（期刊论文）
(14) Saili Duan; Shan Wang; Tao Huang; Junpu Wang*; Xiaoqing Yuan*. circRNAs: Insight into Their Role in Tumor-Associated Macrophages. Frontiers in Oncology, 2021, 11: 780744. (期刊论文,邀稿)
(15) Qiujie Wang, Luna Hong, Ming Chen, Jiangting Shi, Xiaoling Lin, Linjie Huang, Tiantian Tang, Yimin Guo, Xiaoqing Yuan *, Shanping Jiang*. Targeting M2 Macrophages Alleviates Airway Inflammation and Remodeling in Asthmatic Mice via miR-378a-3p/GRB2 Pathway. Frontiers in Molecular Biosciences. 2021 Sep 13; 8:717969.（期刊论文）
(16) Luna Hong, Qiujie Wang, Ming Chen, Jianting Shi, Yimin Guo, Shanying Liu, Ruijian Pan, Xiaoqing Yuan *, Shanping Jiang*. Mas receptor activation attenuates allergic airway inflammation via inhibiting JNK/CCL2-induced macrophage recruitment. Biomedicine & Pharmacotherapy. 2021 May; 137:111365.（期刊论文）
(17) Yimin Guo, Jianting Shi, Qiujie Wang, Luna Hong, Ming Chen, Shanying Liu, Xiaoqing Yuan *, Shanping Jiang*. Metformin alleviates allergic airway inflammation and increases Treg cells in obese asthma. Journal of Cellular and Molecular Medicine. 2021 Feb;25(4):2279-2284. (期刊论文)
(18) Li Peng#, Xiao-Qing Yuan#, Chao-Yang Zhang, Jiang-Yun Peng, Ya-Qin Zhang, Xi Pan and Guan-Cheng Li. The emergence of long non-coding RNAs in hepatocellular carcinoma: an update. Journal of Cancer. 2018; 9(14):2549-2558.（期刊论文）
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